| La Crosse to Effingham (Illinois) | 353.23 mi (568.47 km) |
| La Crosse to Eggertsville (New York) | 625.78 mi (1,007.09 km) |
| La Crosse to Egypt Lake-Leto (Florida) | 1,194.47 mi (1,922.31 km) |
| La Crosse to El Cajon (California) | 1,579.97 mi (2,542.71 km) |
| La Crosse to El Campo (Texas) | 1,048.01 mi (1,686.61 km) |
| La Crosse to El Centro (California) | 1,515.41 mi (2,438.82 km) |
| La Crosse to El Cerrito (California) | 1,663.40 mi (2,676.99 km) |
| La Crosse to El Dorado (Arkansas) | 736.86 mi (1,185.85 km) |
| La Crosse to El Dorado (Kansas) | 508.47 mi (818.30 km) |
| La Crosse to El Dorado Hills (California) | 1,580.31 mi (2,543.27 km) |
| La Crosse to El Mirage (Arizona) | 1,333.56 mi (2,146.16 km) |
| La Crosse to El Monte (California) | 1,580.53 mi (2,543.61 km) |
| La Crosse to El Paso (Texas) | 1,168.08 mi (1,879.84 km) |
| La Crosse to El Paso de Robles (California) | 1,652.29 mi (2,659.11 km) |
| La Crosse to El Reno (Oklahoma) | 674.57 mi (1,085.62 km) |
