| La Crosse to Delaware (Ohio) | 484.15 mi (779.16 km) |
| La Crosse to Delhi (California) | 1,601.67 mi (2,577.64 km) |
| La Crosse to Delray Beach (Florida) | 1,352.08 mi (2,175.97 km) |
| La Crosse to Deltona (Florida) | 1,169.63 mi (1,882.34 km) |
| La Crosse to Deming (New Mexico) | 1,198.64 mi (1,929.02 km) |
| La Crosse to Denison (Texas) | 751.87 mi (1,210.02 km) |
| La Crosse to Dent (Ohio) | 466.51 mi (750.77 km) |
| La Crosse to Denton (Texas) | 799.01 mi (1,285.88 km) |
| La Crosse to Dentsville (South Carolina) | 869.40 mi (1,399.16 km) |
| La Crosse to Denver (Colorado) | 755.90 mi (1,216.50 km) |
| La Crosse to Depew (New York) | 631.52 mi (1,016.33 km) |
| La Crosse to Derby (Connecticut) | 937.13 mi (1,508.16 km) |
| La Crosse to Derby (Kansas) | 535.61 mi (861.98 km) |
| La Crosse to Des Moines (Iowa) | 197.09 mi (317.19 km) |
| La Crosse to Des Moines (Washington) | 1,512.37 mi (2,433.93 km) |
