| La Crosse to Cloverleaf (Texas) | 993.72 mi (1,599.24 km) |
| La Crosse to Cloverly (Maryland) | 804.13 mi (1,294.12 km) |
| La Crosse to Clovis (California) | 1,565.91 mi (2,520.09 km) |
| La Crosse to Clovis (New Mexico) | 910.24 mi (1,464.89 km) |
| La Crosse to Clute (Texas) | 1,048.06 mi (1,686.69 km) |
| La Crosse to Coachella (California) | 1,505.79 mi (2,423.33 km) |
| La Crosse to Coalinga (California) | 1,619.38 mi (2,606.14 km) |
| La Crosse to Coamo (Puerto Rico) | 2,291.12 mi (3,687.20 km) |
| La Crosse to Coatesville (Pennsylvania) | 834.00 mi (1,342.20 km) |
| La Crosse to Cockeysville (Maryland) | 809.76 mi (1,303.19 km) |
| La Crosse to Cocoa (Florida) | 1,213.91 mi (1,953.60 km) |
| La Crosse to Cocoa Beach (Florida) | 1,220.69 mi (1,964.51 km) |
| La Crosse to Coconut Creek (Florida) | 1,360.68 mi (2,189.80 km) |
| La Crosse to Coeur d'Alene (Idaho) | 1,255.02 mi (2,019.76 km) |
| La Crosse to Cohoes (New York) | 882.28 mi (1,419.89 km) |
