| La Carolina to Southern Pines (North Carolina) | 4,079.14 mi (6,564.74 km) |
| La Carolina to Southfield (Michigan) | 4,042.78 mi (6,506.23 km) |
| La Carolina to Southgate (Michigan) | 4,048.23 mi (6,514.99 km) |
| La Carolina to Southlake (Texas) | 5,027.58 mi (8,091.11 km) |
| La Carolina to Spanaway (Washington) | 5,436.93 mi (8,749.89 km) |
| La Carolina to Spanish Fork (Utah) | 5,367.83 mi (8,638.68 km) |
| La Carolina to Spanish Lake (Missouri) | 4,483.44 mi (7,215.40 km) |
| La Carolina to Spanish Springs (Nevada) | 5,703.23 mi (9,178.47 km) |
| La Carolina to Sparks (Nevada) | 5,709.04 mi (9,187.82 km) |
| La Carolina to Spartanburg (South Carolina) | 4,213.14 mi (6,780.39 km) |
| La Carolina to Spearfish (South Dakota) | 4,866.71 mi (7,832.21 km) |
| La Carolina to Speedway (Indiana) | 4,264.57 mi (6,863.16 km) |
| La Carolina to Spencer (Iowa) | 4,553.93 mi (7,328.84 km) |
| La Carolina to Spokane (Washington) | 5,241.29 mi (8,435.04 km) |
| La Carolina to Spokane Valley (Washington) | 5,234.66 mi (8,424.36 km) |
