| Klamath Falls to Southern Pines (North Carolina) | 2,310.92 mi (3,719.07 km) |
| Klamath Falls to Southfield (Michigan) | 1,949.64 mi (3,137.65 km) |
| Klamath Falls to Southgate (Michigan) | 1,956.59 mi (3,148.83 km) |
| Klamath Falls to Southlake (Texas) | 1,485.28 mi (2,390.33 km) |
| Klamath Falls to Spanaway (Washington) | 338.56 mi (544.86 km) |
| Klamath Falls to Spanish Fork (Utah) | 546.56 mi (879.60 km) |
| Klamath Falls to Spanish Lake (Missouri) | 1,665.61 mi (2,680.54 km) |
| Klamath Falls to Spanish Springs (Nevada) | 208.39 mi (335.38 km) |
| Klamath Falls to Sparks (Nevada) | 212.09 mi (341.32 km) |
| Klamath Falls to Spartanburg (South Carolina) | 2,189.27 mi (3,523.29 km) |
| Klamath Falls to Spearfish (South Dakota) | 913.89 mi (1,470.76 km) |
| Klamath Falls to Speedway (Indiana) | 1,846.53 mi (2,971.71 km) |
| Klamath Falls to Spencer (Iowa) | 1,347.99 mi (2,169.38 km) |
| Klamath Falls to Spokane (Washington) | 432.00 mi (695.24 km) |
| Klamath Falls to Spokane Valley (Washington) | 436.57 mi (702.59 km) |
