| Kirkwood to Southern Pines (North Carolina) | 651.67 mi (1,048.76 km) |
| Kirkwood to Southfield (Michigan) | 462.23 mi (743.89 km) |
| Kirkwood to Southgate (Michigan) | 454.61 mi (731.63 km) |
| Kirkwood to Southlake (Texas) | 541.31 mi (871.16 km) |
| Kirkwood to Spanaway (Washington) | 1,710.59 mi (2,752.93 km) |
| Kirkwood to Spanish Fork (Utah) | 1,136.07 mi (1,828.34 km) |
| Kirkwood to Spanish Lake (Missouri) | 18.47 mi (29.73 km) |
| Kirkwood to Spanish Springs (Nevada) | 1,562.76 mi (2,515.02 km) |
| Kirkwood to Sparks (Nevada) | 1,565.91 mi (2,520.09 km) |
| Kirkwood to Spartanburg (South Carolina) | 532.77 mi (857.41 km) |
| Kirkwood to Spearfish (South Dakota) | 802.77 mi (1,291.93 km) |
| Kirkwood to Speedway (Indiana) | 238.66 mi (384.08 km) |
| Kirkwood to Spencer (Iowa) | 400.83 mi (645.07 km) |
| Kirkwood to Spokane (Washington) | 1,489.88 mi (2,397.73 km) |
| Kirkwood to Spokane Valley (Washington) | 1,480.88 mi (2,383.25 km) |
