| Key West to Eugene (Oregon) | 2,677.84 mi (4,309.57 km) |
| Key West to Euless (Texas) | 1,087.99 mi (1,750.96 km) |
| Key West to Eureka (California) | 2,675.16 mi (4,305.25 km) |
| Key West to Eureka (Missouri) | 1,094.13 mi (1,760.83 km) |
| Key West to Eustis (Florida) | 296.62 mi (477.36 km) |
| Key West to Evans (Colorado) | 1,717.98 mi (2,764.82 km) |
| Key West to Evans (Georgia) | 622.05 mi (1,001.10 km) |
| Key West to Evanston (Illinois) | 1,254.45 mi (2,018.84 km) |
| Key West to Evanston (Wyoming) | 2,032.78 mi (3,271.44 km) |
| Key West to Evansville (Indiana) | 987.26 mi (1,588.84 km) |
| Key West to Everett (Massachusetts) | 1,376.24 mi (2,214.85 km) |
| Key West to Everett (Washington) | 2,722.77 mi (4,381.88 km) |
| Key West to Evergreen Park (Illinois) | 1,233.16 mi (1,984.57 km) |
| Key West to Ewa Beach (Hawaii) | 4,791.01 mi (7,710.38 km) |
| Key West to Ewa Gentry (Hawaii) | 4,791.78 mi (7,711.63 km) |
