| Key West to Darby (Pennsylvania) | 1,126.45 mi (1,812.85 km) |
| Key West to Dardenne Prairie (Missouri) | 1,111.61 mi (1,788.97 km) |
| Key West to Darien (Illinois) | 1,239.23 mi (1,994.35 km) |
| Key West to Davenport (Iowa) | 1,278.75 mi (2,057.94 km) |
| Key West to Davidson (North Carolina) | 756.62 mi (1,217.67 km) |
| Key West to Davie (Florida) | 140.06 mi (225.41 km) |
| Key West to Davis (California) | 2,519.22 mi (4,054.30 km) |
| Key West to Dayton (Nevada) | 2,415.13 mi (3,886.78 km) |
| Key West to Dayton (Ohio) | 1,060.73 mi (1,707.08 km) |
| Key West to Daytona Beach (Florida) | 322.99 mi (519.80 km) |
| Key West to De Pere (Wisconsin) | 1,417.65 mi (2,281.48 km) |
| Key West to De Witt (New York) | 1,316.27 mi (2,118.33 km) |
| Key West to Dearborn (Michigan) | 1,229.04 mi (1,977.95 km) |
| Key West to Dearborn Heights (Michigan) | 1,229.54 mi (1,978.76 km) |
| Key West to DeBary (Florida) | 299.61 mi (482.17 km) |
