| Key West to Cloverleaf (Texas) | 898.14 mi (1,445.42 km) |
| Key West to Cloverly (Maryland) | 1,042.73 mi (1,678.12 km) |
| Key West to Clovis (California) | 2,387.45 mi (3,842.23 km) |
| Key West to Clovis (New Mexico) | 1,452.91 mi (2,338.24 km) |
| Key West to Clute (Texas) | 894.05 mi (1,438.83 km) |
| Key West to Coachella (California) | 2,156.55 mi (3,470.63 km) |
| Key West to Coalinga (California) | 2,415.09 mi (3,886.71 km) |
| Key West to Coamo (Puerto Rico) | 1,087.60 mi (1,750.32 km) |
| Key West to Coatesville (Pennsylvania) | 1,120.13 mi (1,802.68 km) |
| Key West to Cockeysville (Maryland) | 1,073.30 mi (1,727.30 km) |
| Key West to Cocoa (Florida) | 271.08 mi (436.25 km) |
| Key West to Cocoa Beach (Florida) | 269.92 mi (434.39 km) |
| Key West to Coconut Creek (Florida) | 154.74 mi (249.02 km) |
| Key West to Coeur d'Alene (Idaho) | 2,489.08 mi (4,005.79 km) |
| Key West to Cohoes (New York) | 1,339.34 mi (2,155.46 km) |
