| Key West to Candler-McAfee (Georgia) | 650.65 mi (1,047.12 km) |
| Key West to Caño Martin Peña (Puerto Rico) | 1,095.19 mi (1,762.54 km) |
| Key West to Cañon City (Colorado) | 1,673.15 mi (2,692.68 km) |
| Key West to Canóvanas (Puerto Rico) | 1,105.89 mi (1,779.76 km) |
| Key West to Canton (Georgia) | 688.54 mi (1,108.09 km) |
| Key West to Canton (Illinois) | 1,204.17 mi (1,937.93 km) |
| Key West to Canton (Mississippi) | 747.00 mi (1,202.19 km) |
| Key West to Canton (Ohio) | 1,122.57 mi (1,806.61 km) |
| Key West to Canyon (Texas) | 1,402.24 mi (2,256.68 km) |
| Key West to Canyon Lake (California) | 2,220.33 mi (3,573.28 km) |
| Key West to Canyon Lake (Texas) | 1,075.92 mi (1,731.53 km) |
| Key West to Cape Coral (Florida) | 144.36 mi (232.33 km) |
| Key West to Cape Girardeau (Missouri) | 993.20 mi (1,598.40 km) |
| Key West to Carbondale (Illinois) | 1,009.22 mi (1,624.19 km) |
| Key West to Carlisle (Pennsylvania) | 1,112.36 mi (1,790.18 km) |
