| Key West to Shoreham-by-Sea | 4,558.29 mi (7,335.85 km) |
| Key West to Shotley Bridge | 4,451.69 mi (7,164.30 km) |
| Key West to Shrewsbury | 4,433.97 mi (7,135.78 km) |
| Key West to Sidcup | 4,567.21 mi (7,350.22 km) |
| Key West to Sidmouth | 4,431.88 mi (7,132.42 km) |
| Key West to Sileby | 4,502.06 mi (7,245.37 km) |
| Key West to Sittingbourne | 4,595.33 mi (7,395.47 km) |
| Key West to Skegness | 4,557.21 mi (7,334.12 km) |
| Key West to Skelmersdale | 4,425.90 mi (7,122.80 km) |
| Key West to Skipton | 4,453.20 mi (7,166.73 km) |
| Key West to Sleaford | 4,527.86 mi (7,286.89 km) |
| Key West to Slough | 4,536.96 mi (7,301.54 km) |
| Key West to Small Heath | 4,473.66 mi (7,199.67 km) |
| Key West to Smethwick | 4,468.61 mi (7,191.53 km) |
| Key West to Snaresbrook | 4,561.58 mi (7,341.15 km) |
