| Keene to Enterprise (Nevada) | 2,312.98 mi (3,722.38 km) |
| Keene to Enumclaw (Washington) | 2,400.89 mi (3,863.87 km) |
| Keene to Ephrata (Pennsylvania) | 277.15 mi (446.03 km) |
| Keene to Erie (Colorado) | 1,695.42 mi (2,728.51 km) |
| Keene to Erie (Pennsylvania) | 399.79 mi (643.40 km) |
| Keene to Erlanger (Kentucky) | 695.40 mi (1,119.13 km) |
| Keene to Escanaba (Michigan) | 754.68 mi (1,214.53 km) |
| Keene to Escondido (California) | 2,497.16 mi (4,018.79 km) |
| Keene to Española (New Mexico) | 1,850.15 mi (2,977.53 km) |
| Keene to Essex (Maryland) | 331.64 mi (533.73 km) |
| Keene to Essex Junction (Vermont) | 113.96 mi (183.40 km) |
| Keene to Estelle (Louisiana) | 1,336.41 mi (2,150.75 km) |
| Keene to Estero (Florida) | 1,260.55 mi (2,028.66 km) |
| Keene to Euclid (Ohio) | 480.35 mi (773.05 km) |
| Keene to Eufaula (Alabama) | 1,036.28 mi (1,667.73 km) |
