| Jeffersonville to Southern Pines (North Carolina) | 410.65 mi (660.88 km) |
| Jeffersonville to Southfield (Michigan) | 313.47 mi (504.48 km) |
| Jeffersonville to Southgate (Michigan) | 297.82 mi (479.29 km) |
| Jeffersonville to Southlake (Texas) | 741.78 mi (1,193.78 km) |
| Jeffersonville to Spanaway (Washington) | 1,939.43 mi (3,121.21 km) |
| Jeffersonville to Spanish Fork (Utah) | 1,388.78 mi (2,235.03 km) |
| Jeffersonville to Spanish Lake (Missouri) | 245.35 mi (394.85 km) |
| Jeffersonville to Spanish Springs (Nevada) | 1,815.32 mi (2,921.48 km) |
| Jeffersonville to Sparks (Nevada) | 1,818.60 mi (2,926.76 km) |
| Jeffersonville to Spartanburg (South Carolina) | 314.31 mi (505.83 km) |
| Jeffersonville to Spearfish (South Dakota) | 1,027.41 mi (1,653.46 km) |
| Jeffersonville to Speedway (Indiana) | 104.78 mi (168.62 km) |
| Jeffersonville to Spencer (Iowa) | 595.38 mi (958.17 km) |
| Jeffersonville to Spokane (Washington) | 1,713.11 mi (2,756.99 km) |
| Jeffersonville to Spokane Valley (Washington) | 1,703.98 mi (2,742.29 km) |
