| James Island to Worthington (Ohio) | 536.49 mi (863.40 km) |
| James Island to Wright (Florida) | 424.94 mi (683.87 km) |
| James Island to Wyandanch (New York) | 662.24 mi (1,065.77 km) |
| James Island to Wyandotte (Michigan) | 677.92 mi (1,091.01 km) |
| James Island to Wylie (Texas) | 961.03 mi (1,546.63 km) |
| James Island to Wyndham (Virginia) | 366.79 mi (590.30 km) |
| James Island to Wyoming (Michigan) | 768.56 mi (1,236.88 km) |
| James Island to Wyomissing (Pennsylvania) | 569.07 mi (915.83 km) |
| James Island to Xenia (Ohio) | 529.19 mi (851.65 km) |
| James Island to Yakima (Washington) | 2,330.42 mi (3,750.44 km) |
| James Island to Yankton (South Dakota) | 1,179.22 mi (1,897.77 km) |
| James Island to Yauco (Puerto Rico) | 1,300.56 mi (2,093.05 km) |
| James Island to Yazoo City (Mississippi) | 607.78 mi (978.14 km) |
| James Island to Yeadon (Pennsylvania) | 561.33 mi (903.37 km) |
| James Island to Yelm (Washington) | 2,431.23 mi (3,912.68 km) |
