| James Island to The Villages (Florida) | 291.33 mi (468.85 km) |
| James Island to The Woodlands (Texas) | 933.92 mi (1,503.00 km) |
| James Island to Thibodaux (Louisiana) | 673.26 mi (1,083.50 km) |
| James Island to Thomasville (Georgia) | 270.93 mi (436.03 km) |
| James Island to Thomasville (North Carolina) | 217.52 mi (350.06 km) |
| James Island to Thonotosassa (Florida) | 352.96 mi (568.03 km) |
| James Island to Thornton (Colorado) | 1,471.77 mi (2,368.59 km) |
| James Island to Thousand Oaks (California) | 2,232.88 mi (3,593.48 km) |
| James Island to Three Lakes (Florida) | 490.92 mi (790.06 km) |
| James Island to Tiffin (Ohio) | 605.99 mi (975.25 km) |
| James Island to Tifton (Georgia) | 227.28 mi (365.77 km) |
| James Island to Tigard (Oregon) | 2,425.79 mi (3,903.93 km) |
| James Island to Tillmans Corner (Alabama) | 508.64 mi (818.58 km) |
| James Island to Timberlake (Virginia) | 318.95 mi (513.30 km) |
| James Island to Timberlane (Louisiana) | 627.24 mi (1,009.44 km) |
