| James Island to Stephenville (Texas) | 1,064.87 mi (1,713.75 km) |
| James Island to Sterling (Colorado) | 1,393.53 mi (2,242.67 km) |
| James Island to Sterling (Illinois) | 823.47 mi (1,325.25 km) |
| James Island to Sterling (Virginia) | 455.80 mi (733.54 km) |
| James Island to Sterling Heights (Michigan) | 700.82 mi (1,127.86 km) |
| James Island to Steubenville (Ohio) | 528.66 mi (850.79 km) |
| James Island to Stevens Point (Wisconsin) | 964.14 mi (1,551.63 km) |
| James Island to Stevenson Ranch (California) | 2,214.67 mi (3,564.16 km) |
| James Island to Stillwater (Minnesota) | 1,095.05 mi (1,762.31 km) |
| James Island to Stillwater (Oklahoma) | 1,002.79 mi (1,613.83 km) |
| James Island to Stockbridge (Georgia) | 254.14 mi (409.00 km) |
| James Island to Stockton (California) | 2,339.91 mi (3,765.73 km) |
| James Island to Stone Ridge (Virginia) | 448.27 mi (721.42 km) |
| James Island to Stonecrest (Georgia) | 251.35 mi (404.50 km) |
| James Island to Stony Brook (New York) | 678.20 mi (1,091.45 km) |
