| James Island to Sanford (Maine) | 890.27 mi (1,432.74 km) |
| James Island to Sanford (North Carolina) | 195.09 mi (313.97 km) |
| James Island to Sanger (California) | 2,250.65 mi (3,622.07 km) |
| James Island to Santa Ana (California) | 2,181.38 mi (3,510.58 km) |
| James Island to Santa Barbara (California) | 2,278.12 mi (3,666.28 km) |
| James Island to Santa Clara (California) | 2,379.07 mi (3,828.74 km) |
| James Island to Santa Clara (Oregon) | 2,435.17 mi (3,919.02 km) |
| James Island to Santa Clarita (California) | 2,209.21 mi (3,555.38 km) |
| James Island to Santa Cruz (California) | 2,385.24 mi (3,838.67 km) |
| James Island to Santa Fe (New Mexico) | 1,497.47 mi (2,409.94 km) |
| James Island to Santa Fe (Texas) | 925.69 mi (1,489.75 km) |
| James Island to Santa Fe Springs (California) | 2,189.54 mi (3,523.73 km) |
| James Island to Santa Maria (California) | 2,313.75 mi (3,723.62 km) |
| James Island to Santa Monica (California) | 2,212.30 mi (3,560.36 km) |
| James Island to Santa Paula (California) | 2,241.95 mi (3,608.07 km) |
