| James Island to Saddlebrooke (Arizona) | 1,793.25 mi (2,885.96 km) |
| James Island to Safety Harbor (Florida) | 365.60 mi (588.37 km) |
| James Island to Saginaw (Michigan) | 769.53 mi (1,238.44 km) |
| James Island to Saginaw (Texas) | 1,010.94 mi (1,626.95 km) |
| James Island to Sahuarita (Arizona) | 1,805.66 mi (2,905.93 km) |
| James Island to Saks (Alabama) | 348.38 mi (560.66 km) |
| James Island to Salem (Massachusetts) | 836.14 mi (1,345.64 km) |
| James Island to Salem (Ohio) | 566.69 mi (912.00 km) |
| James Island to Salem (Oregon) | 2,434.10 mi (3,917.30 km) |
| James Island to Salem (Virginia) | 314.52 mi (506.17 km) |
| James Island to Salem Lakes (Wisconsin) | 811.16 mi (1,305.44 km) |
| James Island to Salida (California) | 2,328.88 mi (3,747.96 km) |
| James Island to Salina (Kansas) | 1,073.79 mi (1,728.10 km) |
| James Island to Salinas (California) | 2,365.11 mi (3,806.28 km) |
| James Island to Salisbury (Maryland) | 460.01 mi (740.31 km) |
