| James Island to Reidsville (North Carolina) | 249.36 mi (401.30 km) |
| James Island to Reisterstown (Maryland) | 495.90 mi (798.07 km) |
| James Island to Rendon (Texas) | 1,005.03 mi (1,617.44 km) |
| James Island to Reno (Nevada) | 2,256.85 mi (3,632.04 km) |
| James Island to Renton (Washington) | 2,416.77 mi (3,889.42 km) |
| James Island to Republic (Missouri) | 822.40 mi (1,323.53 km) |
| James Island to Reston (Virginia) | 453.22 mi (729.38 km) |
| James Island to Revere (Massachusetts) | 827.83 mi (1,332.26 km) |
| James Island to Rexburg (Idaho) | 1,874.78 mi (3,017.17 km) |
| James Island to Reynoldsburg (Ohio) | 523.69 mi (842.79 km) |
| James Island to Rialto (California) | 2,149.54 mi (3,459.35 km) |
| James Island to Richardson (Texas) | 972.48 mi (1,565.05 km) |
| James Island to Richfield (Minnesota) | 1,101.47 mi (1,772.65 km) |
| James Island to Richfield (Wisconsin) | 853.90 mi (1,374.21 km) |
| James Island to Richland (Washington) | 2,267.83 mi (3,649.73 km) |
