| James Island to Oswego (Illinois) | 771.01 mi (1,240.83 km) |
| James Island to Oswego (New York) | 763.48 mi (1,228.70 km) |
| James Island to Otsego (Minnesota) | 1,132.16 mi (1,822.03 km) |
| James Island to Ottawa (Illinois) | 770.40 mi (1,239.83 km) |
| James Island to Ottawa (Kansas) | 949.18 mi (1,527.56 km) |
| James Island to Ottumwa (Iowa) | 894.66 mi (1,439.82 km) |
| James Island to Overland (Missouri) | 714.74 mi (1,150.26 km) |
| James Island to Overland Park (Kansas) | 927.63 mi (1,492.88 km) |
| James Island to Overlea (Maryland) | 496.19 mi (798.54 km) |
| James Island to Oviedo (Florida) | 291.30 mi (468.80 km) |
| James Island to Owasso (Oklahoma) | 936.23 mi (1,506.72 km) |
| James Island to Owatonna (Minnesota) | 1,061.90 mi (1,708.96 km) |
| James Island to Owensboro (Kentucky) | 533.03 mi (857.82 km) |
| James Island to Owings Mills (Maryland) | 493.55 mi (794.30 km) |
| James Island to Owosso (Michigan) | 745.35 mi (1,199.52 km) |
