| James Island to Odessa (Texas) | 1,307.31 mi (2,103.91 km) |
| James Island to Ogden (Utah) | 1,850.39 mi (2,977.92 km) |
| James Island to Oildale (California) | 2,230.25 mi (3,589.24 km) |
| James Island to Ojus (Florida) | 468.57 mi (754.09 km) |
| James Island to Okemos (Michigan) | 730.70 mi (1,175.95 km) |
| James Island to Oklahoma City (Oklahoma) | 1,021.58 mi (1,644.08 km) |
| James Island to Okmulgee (Oklahoma) | 938.59 mi (1,510.51 km) |
| James Island to Olathe (Kansas) | 934.13 mi (1,503.34 km) |
| James Island to Old Jamestown (Missouri) | 716.21 mi (1,152.63 km) |
| James Island to Oldsmar (Florida) | 362.24 mi (582.97 km) |
| James Island to Olean (New York) | 651.03 mi (1,047.73 km) |
| James Island to Olive Branch (Mississippi) | 588.66 mi (947.36 km) |
| James Island to Olivehurst (California) | 2,349.00 mi (3,780.35 km) |
| James Island to Olney (Maryland) | 471.05 mi (758.08 km) |
| James Island to Olympia (Washington) | 2,444.81 mi (3,934.54 km) |
