| James Island to Medford (New York) | 677.90 mi (1,090.97 km) |
| James Island to Medford (Oregon) | 2,415.31 mi (3,887.07 km) |
| James Island to Medina (Ohio) | 590.08 mi (949.64 km) |
| James Island to Medulla (Florida) | 351.97 mi (566.44 km) |
| James Island to Mehlville (Missouri) | 705.20 mi (1,134.91 km) |
| James Island to Melbourne (Florida) | 322.56 mi (519.11 km) |
| James Island to Melissa (Texas) | 962.56 mi (1,549.09 km) |
| James Island to Melrose (Massachusetts) | 828.04 mi (1,332.61 km) |
| James Island to Melrose Park (Illinois) | 767.85 mi (1,235.74 km) |
| James Island to Melville (New York) | 662.72 mi (1,066.54 km) |
| James Island to Melvindale (Michigan) | 682.81 mi (1,098.88 km) |
| James Island to Memphis (Florida) | 391.38 mi (629.87 km) |
| James Island to Memphis (Tennessee) | 597.50 mi (961.58 km) |
| James Island to Menasha (Wisconsin) | 915.12 mi (1,472.74 km) |
| James Island to Mendota (California) | 2,295.54 mi (3,694.31 km) |
