| James Island to McKeesport (Pennsylvania) | 525.58 mi (845.85 km) |
| James Island to McKinleyville (California) | 2,478.70 mi (3,989.09 km) |
| James Island to McKinney (Texas) | 969.16 mi (1,559.71 km) |
| James Island to McLean (Virginia) | 455.61 mi (733.23 km) |
| James Island to McMinnville (Oregon) | 2,444.03 mi (3,933.29 km) |
| James Island to McMinnville (Tennessee) | 391.03 mi (629.30 km) |
| James Island to McNair (Virginia) | 452.16 mi (727.69 km) |
| James Island to McPherson (Kansas) | 1,067.35 mi (1,717.74 km) |
| James Island to Mead Valley (California) | 2,146.49 mi (3,454.45 km) |
| James Island to Meadow Woods (Florida) | 313.02 mi (503.76 km) |
| James Island to Meadowbrook (Virginia) | 353.02 mi (568.14 km) |
| James Island to Meadville (Pennsylvania) | 615.89 mi (991.17 km) |
| James Island to Mebane (North Carolina) | 234.54 mi (377.46 km) |
| James Island to Mechanicsville (Virginia) | 368.03 mi (592.29 km) |
| James Island to Medford (Massachusetts) | 824.72 mi (1,327.26 km) |
