| James Island to Lowell (Indiana) | 720.32 mi (1,159.25 km) |
| James Island to Lowell (Massachusetts) | 829.79 mi (1,335.42 km) |
| James Island to Lower Burrell (Pennsylvania) | 542.28 mi (872.72 km) |
| James Island to Lowes Island (Virginia) | 459.46 mi (739.42 km) |
| James Island to Lubbock (Texas) | 1,268.59 mi (2,041.60 km) |
| James Island to Lufkin (Texas) | 871.01 mi (1,401.75 km) |
| James Island to Luling (Louisiana) | 644.74 mi (1,037.60 km) |
| James Island to Lumberton (North Carolina) | 141.29 mi (227.38 km) |
| James Island to Lumberton (Texas) | 857.12 mi (1,379.40 km) |
| James Island to Lutz (Florida) | 350.87 mi (564.67 km) |
| James Island to Lynbrook (New York) | 647.74 mi (1,042.43 km) |
| James Island to Lynchburg (Virginia) | 325.08 mi (523.17 km) |
| James Island to Lynden (Washington) | 2,446.84 mi (3,937.80 km) |
| James Island to Lyndhurst (Ohio) | 612.74 mi (986.11 km) |
| James Island to Lyndon (Kentucky) | 496.70 mi (799.37 km) |
