| Ithaca to Silver Firs (Washington) | 2,222.13 mi (3,576.18 km) |
| Ithaca to Silver Spring (Maryland) | 239.32 mi (385.14 km) |
| Ithaca to Silver Springs Shores (Florida) | 970.98 mi (1,562.63 km) |
| Ithaca to Silverdale (Washington) | 2,248.53 mi (3,618.66 km) |
| Ithaca to Silverton (Oregon) | 2,285.95 mi (3,678.88 km) |
| Ithaca to Simi Valley (California) | 2,332.16 mi (3,753.25 km) |
| Ithaca to Simpsonville (South Carolina) | 616.68 mi (992.45 km) |
| Ithaca to Sioux City (Iowa) | 1,011.22 mi (1,627.39 km) |
| Ithaca to Sioux Falls (South Dakota) | 1,022.55 mi (1,645.63 km) |
| Ithaca to Skokie (Illinois) | 575.06 mi (925.47 km) |
| Ithaca to Sleepy Hollow (New York) | 164.58 mi (264.86 km) |
| Ithaca to Slidell (Louisiana) | 1,115.79 mi (1,795.69 km) |
| Ithaca to Smithfield (North Carolina) | 489.00 mi (786.97 km) |
| Ithaca to Smithfield (Utah) | 1,797.06 mi (2,892.08 km) |
| Ithaca to Smithville (Missouri) | 964.80 mi (1,552.69 km) |
