| Rome to Sarzana | 199.45 mi (320.98 km) |
| Rome to Sassari | 218.97 mi (352.40 km) |
| Rome to Sasso Marconi | 184.02 mi (296.14 km) |
| Rome to Sassuolo | 202.58 mi (326.02 km) |
| Rome to Sava | 283.85 mi (456.81 km) |
| Rome to Saviano | 125.14 mi (201.39 km) |
| Rome to Savigliano | 309.43 mi (497.98 km) |
| Rome to Savignano sul Panaro | 193.28 mi (311.05 km) |
| Rome to Savignano sul Rubicone | 151.73 mi (244.18 km) |
| Rome to Savona | 261.86 mi (421.42 km) |
| Rome to Scafati | 132.02 mi (212.47 km) |
| Rome to Scalea | 224.99 mi (362.09 km) |
| Rome to Scandiano | 207.23 mi (333.50 km) |
| Rome to Scandicci | 144.34 mi (232.29 km) |
| Rome to Schio | 269.71 mi (434.06 km) |
