| Issoudun to Reidsville (North Carolina) | 4,087.30 mi (6,577.87 km) |
| Issoudun to Reisterstown (Maryland) | 3,833.38 mi (6,169.23 km) |
| Issoudun to Rendon (Texas) | 5,007.12 mi (8,058.18 km) |
| Issoudun to Reno (Nevada) | 5,471.35 mi (8,805.29 km) |
| Issoudun to Renton (Washington) | 5,097.69 mi (8,203.94 km) |
| Issoudun to Republic (Missouri) | 4,633.78 mi (7,457.35 km) |
| Issoudun to Reston (Virginia) | 3,876.92 mi (6,239.30 km) |
| Issoudun to Revere (Massachusetts) | 3,467.60 mi (5,580.56 km) |
| Issoudun to Rexburg (Idaho) | 4,981.70 mi (8,017.27 km) |
| Issoudun to Reynoldsburg (Ohio) | 4,068.17 mi (6,547.08 km) |
| Issoudun to Rialto (California) | 5,692.03 mi (9,160.44 km) |
| Issoudun to Richardson (Texas) | 4,966.34 mi (7,992.55 km) |
| Issoudun to Richfield (Minnesota) | 4,276.45 mi (6,882.28 km) |
| Issoudun to Richfield (Wisconsin) | 4,152.30 mi (6,682.49 km) |
| Issoudun to Richland (Washington) | 5,082.02 mi (8,178.72 km) |
