| Issoudun to Shotley Bridge | 572.29 mi (921.02 km) |
| Issoudun to Shrewsbury | 450.49 mi (724.99 km) |
| Issoudun to Sidcup | 320.95 mi (516.52 km) |
| Issoudun to Sidmouth | 350.77 mi (564.51 km) |
| Issoudun to Sileby | 422.65 mi (680.19 km) |
| Issoudun to Sittingbourne | 308.68 mi (496.77 km) |
| Issoudun to Skegness | 434.25 mi (698.87 km) |
| Issoudun to Skelmersdale | 502.19 mi (808.20 km) |
| Issoudun to Skipton | 515.54 mi (829.67 km) |
| Issoudun to Sleaford | 431.27 mi (694.06 km) |
| Issoudun to Slough | 335.87 mi (540.53 km) |
| Issoudun to Small Heath | 417.88 mi (672.51 km) |
| Issoudun to Smethwick | 421.86 mi (678.93 km) |
| Issoudun to Snaresbrook | 332.67 mi (535.38 km) |
| Issoudun to Snodland | 310.57 mi (499.82 km) |
