| Issoire to Somma Lombardo | 263.58 mi (424.19 km) |
| Issoire to Somma Vesuviana | 648.48 mi (1,043.62 km) |
| Issoire to Sommacampagna | 368.29 mi (592.70 km) |
| Issoire to Sona | 367.31 mi (591.14 km) |
| Issoire to Sondrio | 321.43 mi (517.29 km) |
| Issoire to Sora | 581.42 mi (935.71 km) |
| Issoire to Sorbolo | 353.73 mi (569.27 km) |
| Issoire to Soresina | 320.90 mi (516.44 km) |
| Issoire to Sorisole | 309.73 mi (498.46 km) |
| Issoire to Sorrento | 655.25 mi (1,054.52 km) |
| Issoire to Sorso | 423.60 mi (681.73 km) |
| Issoire to Sortino | 840.11 mi (1,352.03 km) |
| Issoire to Soverato Marina | 828.63 mi (1,333.55 km) |
| Issoire to Sovicille | 423.66 mi (681.81 km) |
| Issoire to Spello | 498.17 mi (801.73 km) |
