| Isabela to Sangeorgiu de Mures | 5,367.05 mi (8,637.43 km) |
| Isabela to Sangeorz-Bai | 5,363.13 mi (8,631.13 km) |
| Isabela to Sannicolau Mare | 5,195.01 mi (8,360.56 km) |
| Isabela to Santana | 5,232.54 mi (8,420.97 km) |
| Isabela to Satu Mare | 5,275.27 mi (8,489.73 km) |
| Isabela to Scobinti | 5,464.85 mi (8,794.83 km) |
| Isabela to Scornicesti | 5,404.56 mi (8,697.80 km) |
| Isabela to Sebes | 5,335.12 mi (8,586.04 km) |
| Isabela to Seini | 5,293.82 mi (8,519.58 km) |
| Isabela to Sfantu-Gheorghe | 5,440.07 mi (8,754.95 km) |
| Isabela to Sibiu | 5,365.05 mi (8,634.21 km) |
| Isabela to Sighetu Marmatiei | 5,318.42 mi (8,559.17 km) |
| Isabela to Sighisoara | 5,387.66 mi (8,670.60 km) |
| Isabela to Simeria | 5,310.67 mi (8,546.70 km) |
| Isabela to Sinaia | 5,438.23 mi (8,751.99 km) |
