| Irving to Southern Pines (North Carolina) | 1,017.37 mi (1,637.30 km) |
| Irving to Southfield (Michigan) | 999.58 mi (1,608.67 km) |
| Irving to Southgate (Michigan) | 990.61 mi (1,594.23 km) |
| Irving to Southlake (Texas) | 12.38 mi (19.93 km) |
| Irving to Spanaway (Washington) | 1,656.04 mi (2,665.14 km) |
| Irving to Spanish Fork (Utah) | 954.78 mi (1,536.56 km) |
| Irving to Spanish Lake (Missouri) | 557.69 mi (897.52 km) |
| Irving to Spanish Springs (Nevada) | 1,344.53 mi (2,163.81 km) |
| Irving to Sparks (Nevada) | 1,345.64 mi (2,165.59 km) |
| Irving to Spartanburg (South Carolina) | 873.88 mi (1,406.37 km) |
| Irving to Spearfish (South Dakota) | 883.68 mi (1,422.15 km) |
| Irving to Speedway (Indiana) | 764.43 mi (1,230.23 km) |
| Irving to Spencer (Iowa) | 717.66 mi (1,154.97 km) |
| Irving to Spokane (Washington) | 1,478.24 mi (2,379.00 km) |
| Irving to Spokane Valley (Washington) | 1,470.64 mi (2,366.77 km) |
