| Irvine to The Villages (Florida) | 4,111.92 mi (6,617.49 km) |
| Irvine to The Woodlands (Texas) | 4,556.58 mi (7,333.10 km) |
| Irvine to Thibodaux (Louisiana) | 4,401.69 mi (7,083.83 km) |
| Irvine to Thomasville (Georgia) | 4,086.09 mi (6,575.93 km) |
| Irvine to Thomasville (North Carolina) | 3,676.38 mi (5,916.56 km) |
| Irvine to Thonotosassa (Florida) | 4,169.26 mi (6,709.77 km) |
| Irvine to Thornton (Colorado) | 4,360.34 mi (7,017.30 km) |
| Irvine to Thousand Oaks (California) | 5,126.98 mi (8,251.07 km) |
| Irvine to Three Lakes (Florida) | 4,224.91 mi (6,799.33 km) |
| Irvine to Tiffin (Ohio) | 3,533.56 mi (5,686.72 km) |
| Irvine to Tifton (Georgia) | 4,035.77 mi (6,494.94 km) |
| Irvine to Tigard (Oregon) | 4,584.68 mi (7,378.34 km) |
| Irvine to Tillmans Corner (Alabama) | 4,261.24 mi (6,857.81 km) |
| Irvine to Timberlake (Virginia) | 3,572.63 mi (5,749.59 km) |
| Irvine to Timberlane (Louisiana) | 4,367.63 mi (7,029.03 km) |
