| Irvine to South Plainfield (New Jersey) | 3,229.80 mi (5,197.86 km) |
| Irvine to South Portland (Maine) | 2,931.45 mi (4,717.71 km) |
| Irvine to South Riding (Virginia) | 3,427.92 mi (5,516.70 km) |
| Irvine to South River (New Jersey) | 3,234.53 mi (5,205.47 km) |
| Irvine to South Salt Lake (Utah) | 4,539.93 mi (7,306.31 km) |
| Irvine to South San Francisco (California) | 5,028.96 mi (8,093.33 km) |
| Irvine to South San Jose Hills (California) | 5,107.54 mi (8,219.79 km) |
| Irvine to South Sioux City (Nebraska) | 3,939.23 mi (6,339.57 km) |
| Irvine to South St. Paul (Minnesota) | 3,701.77 mi (5,957.42 km) |
| Irvine to South Valley (New Mexico) | 4,687.41 mi (7,543.65 km) |
| Irvine to South Venice (Florida) | 4,227.72 mi (6,803.85 km) |
| Irvine to South Whittier (California) | 5,116.04 mi (8,233.47 km) |
| Irvine to South Yarmouth (Massachusetts) | 3,017.17 mi (4,855.67 km) |
| Irvine to Southaven (Mississippi) | 4,097.01 mi (6,593.50 km) |
| Irvine to Southchase (Florida) | 4,116.63 mi (6,625.07 km) |
