| Irvine to Oxford (Alabama) | 4,013.67 mi (6,459.37 km) |
| Irvine to Oxford (Mississippi) | 4,111.26 mi (6,616.44 km) |
| Irvine to Oxford (Ohio) | 3,670.62 mi (5,907.30 km) |
| Irvine to Oxnard (California) | 5,136.03 mi (8,265.64 km) |
| Irvine to Oxon Hill (Maryland) | 3,413.34 mi (5,493.24 km) |
| Irvine to Ozark (Alabama) | 4,117.68 mi (6,626.77 km) |
| Irvine to Ozark (Missouri) | 4,106.74 mi (6,609.16 km) |
| Irvine to Pace (Florida) | 4,219.55 mi (6,790.71 km) |
| Irvine to Pacific Grove (California) | 5,075.66 mi (8,168.49 km) |
| Irvine to Pacifica (California) | 5,033.14 mi (8,100.05 km) |
| Irvine to Paducah (Kentucky) | 3,937.87 mi (6,337.39 km) |
| Irvine to Pahrump (Nevada) | 4,920.69 mi (7,919.09 km) |
| Irvine to Painesville (Ohio) | 3,432.81 mi (5,524.57 km) |
| Irvine to Palatine (Illinois) | 3,662.12 mi (5,893.62 km) |
| Irvine to Palatka (Florida) | 4,060.08 mi (6,534.06 km) |
