| Irvine to Mendota Heights (Minnesota) | 3,705.47 mi (5,963.38 km) |
| Irvine to Menifee (California) | 5,103.85 mi (8,213.86 km) |
| Irvine to Menlo Park (California) | 5,032.63 mi (8,099.24 km) |
| Irvine to Menomonee Falls (Wisconsin) | 3,614.52 mi (5,817.00 km) |
| Irvine to Menomonie (Wisconsin) | 3,662.66 mi (5,894.49 km) |
| Irvine to Mentor (Ohio) | 3,437.54 mi (5,532.19 km) |
| Irvine to Mequon (Wisconsin) | 3,605.35 mi (5,802.24 km) |
| Irvine to Merced (California) | 4,993.12 mi (8,035.65 km) |
| Irvine to Mercedes (Texas) | 4,865.95 mi (7,830.99 km) |
| Irvine to Mercer Island (Washington) | 4,446.56 mi (7,156.05 km) |
| Irvine to Mercerville (New Jersey) | 3,256.46 mi (5,240.77 km) |
| Irvine to Meriden (Connecticut) | 3,122.69 mi (5,025.49 km) |
| Irvine to Meridian (Idaho) | 4,511.81 mi (7,261.06 km) |
| Irvine to Meridian (Mississippi) | 4,183.67 mi (6,732.97 km) |
| Irvine to Merriam (Kansas) | 4,056.56 mi (6,528.41 km) |
