| Irvine to Mauldin (South Carolina) | 3,817.07 mi (6,142.99 km) |
| Irvine to Maumee (Ohio) | 3,529.40 mi (5,680.02 km) |
| Irvine to Maumelle (Arkansas) | 4,191.53 mi (6,745.61 km) |
| Irvine to Mayagüez (Puerto Rico) | 4,119.71 mi (6,630.03 km) |
| Irvine to Mayfield Heights (Ohio) | 3,450.15 mi (5,552.48 km) |
| Irvine to Mays Chapel (Maryland) | 3,369.72 mi (5,423.05 km) |
| Irvine to Maywood (California) | 5,117.67 mi (8,236.09 km) |
| Irvine to Maywood (Illinois) | 3,666.68 mi (5,900.95 km) |
| Irvine to McAlester (Oklahoma) | 4,310.43 mi (6,936.97 km) |
| Irvine to McAllen (Texas) | 4,874.35 mi (7,844.50 km) |
| Irvine to McCalla (Alabama) | 4,072.91 mi (6,554.72 km) |
| Irvine to McComb (Mississippi) | 4,311.18 mi (6,938.17 km) |
| Irvine to McDonough (Georgia) | 3,956.63 mi (6,367.58 km) |
| Irvine to McFarland (California) | 5,051.35 mi (8,129.37 km) |
| Irvine to McHenry (Illinois) | 3,660.27 mi (5,890.63 km) |
