| Irvine to Lowell (Indiana) | 3,680.32 mi (5,922.91 km) |
| Irvine to Lowell (Massachusetts) | 3,015.64 mi (4,853.20 km) |
| Irvine to Lower Burrell (Pennsylvania) | 3,430.20 mi (5,520.38 km) |
| Irvine to Lowes Island (Virginia) | 3,415.21 mi (5,496.25 km) |
| Irvine to Lubbock (Texas) | 4,601.73 mi (7,405.77 km) |
| Irvine to Lufkin (Texas) | 4,465.45 mi (7,186.44 km) |
| Irvine to Luling (Louisiana) | 4,378.57 mi (7,046.63 km) |
| Irvine to Lumberton (North Carolina) | 3,699.06 mi (5,953.06 km) |
| Irvine to Lumberton (Texas) | 4,503.73 mi (7,248.06 km) |
| Irvine to Lutz (Florida) | 4,170.31 mi (6,711.46 km) |
| Irvine to Lynbrook (New York) | 3,197.55 mi (5,145.97 km) |
| Irvine to Lynchburg (Virginia) | 3,566.29 mi (5,739.39 km) |
| Irvine to Lynden (Washington) | 4,372.86 mi (7,037.43 km) |
| Irvine to Lyndhurst (Ohio) | 3,451.60 mi (5,554.81 km) |
| Irvine to Lyndon (Kentucky) | 3,764.05 mi (6,057.65 km) |
