| Irvine to Livermore (California) | 5,008.10 mi (8,059.75 km) |
| Irvine to Livingston (California) | 4,995.57 mi (8,039.59 km) |
| Irvine to Livonia (Michigan) | 3,478.80 mi (5,598.58 km) |
| Irvine to Lochearn (Maryland) | 3,377.01 mi (5,434.77 km) |
| Irvine to Lockhart (Florida) | 4,105.20 mi (6,606.67 km) |
| Irvine to Lockhart (Texas) | 4,652.45 mi (7,487.40 km) |
| Irvine to Lockport (Illinois) | 3,687.63 mi (5,934.67 km) |
| Irvine to Lockport (New York) | 3,269.36 mi (5,261.52 km) |
| Irvine to Lodi (California) | 4,969.11 mi (7,997.00 km) |
| Irvine to Lodi (New Jersey) | 3,202.70 mi (5,154.25 km) |
| Irvine to Logan (Utah) | 4,480.70 mi (7,210.99 km) |
| Irvine to Logansport (Indiana) | 3,668.34 mi (5,903.62 km) |
| Irvine to Loganville (Georgia) | 3,926.44 mi (6,318.99 km) |
| Irvine to Loma Linda (California) | 5,085.34 mi (8,184.06 km) |
| Irvine to Lombard (Illinois) | 3,673.15 mi (5,911.36 km) |
