| Irvine to Lemay (Missouri) | 3,923.16 mi (6,313.72 km) |
| Irvine to Lemon Grove (California) | 5,154.74 mi (8,295.75 km) |
| Irvine to Lemon Hill (California) | 4,950.68 mi (7,967.35 km) |
| Irvine to Lemont (Illinois) | 3,682.09 mi (5,925.75 km) |
| Irvine to Lemoore (California) | 5,032.06 mi (8,098.32 km) |
| Irvine to Lenexa (Kansas) | 4,063.41 mi (6,539.42 km) |
| Irvine to Lennox (California) | 5,125.88 mi (8,249.31 km) |
| Irvine to Lenoir (North Carolina) | 3,730.02 mi (6,002.88 km) |
| Irvine to Leominster (Massachusetts) | 3,038.21 mi (4,889.52 km) |
| Irvine to Leon Valley (Texas) | 4,707.49 mi (7,575.97 km) |
| Irvine to Levelland (Texas) | 4,617.60 mi (7,431.31 km) |
| Irvine to Levittown (New York) | 3,188.25 mi (5,130.98 km) |
| Irvine to Levittown (Pennsylvania) | 3,266.57 mi (5,257.03 km) |
| Irvine to Lewisburg (Tennessee) | 3,952.26 mi (6,360.55 km) |
| Irvine to Lewiston (Idaho) | 4,372.28 mi (7,036.50 km) |
