| Irvine to La Crosse (Wisconsin) | 3,691.23 mi (5,940.46 km) |
| Irvine to La Grande (Oregon) | 4,462.97 mi (7,182.45 km) |
| Irvine to La Grange (Illinois) | 3,671.34 mi (5,908.45 km) |
| Irvine to La Grange Park (Illinois) | 3,670.11 mi (5,906.47 km) |
| Irvine to La Habra (California) | 5,113.89 mi (8,230.01 km) |
| Irvine to La Homa (Texas) | 4,875.44 mi (7,846.25 km) |
| Irvine to La Marque (Texas) | 4,581.12 mi (7,372.60 km) |
| Irvine to La Mesa (California) | 5,152.14 mi (8,291.56 km) |
| Irvine to La Mirada (California) | 5,117.17 mi (8,235.29 km) |
| Irvine to La Palma (California) | 5,121.17 mi (8,241.73 km) |
| Irvine to La Porte (Indiana) | 3,639.19 mi (5,856.70 km) |
| Irvine to La Porte (Texas) | 4,566.79 mi (7,349.55 km) |
| Irvine to La Presa (California) | 5,155.02 mi (8,296.21 km) |
| Irvine to La Puente (California) | 5,107.89 mi (8,220.35 km) |
| Irvine to La Quinta (California) | 5,077.60 mi (8,171.60 km) |
