| Irvine to Iselin (New Jersey) | 3,226.30 mi (5,192.23 km) |
| Irvine to Isla Vista (California) | 5,144.01 mi (8,278.48 km) |
| Irvine to Issaquah (Washington) | 4,443.05 mi (7,150.39 km) |
| Irvine to Ithaca (New York) | 3,221.10 mi (5,183.86 km) |
| Irvine to Ives Estates (Florida) | 4,199.12 mi (6,757.83 km) |
| Irvine to Jackson (Michigan) | 3,523.97 mi (5,671.28 km) |
| Irvine to Jackson (Mississippi) | 4,244.47 mi (6,830.82 km) |
| Irvine to Jackson (Missouri) | 3,959.16 mi (6,371.65 km) |
| Irvine to Jackson (Tennessee) | 4,018.05 mi (6,466.43 km) |
| Irvine to Jackson (Wyoming) | 4,352.47 mi (7,004.62 km) |
| Irvine to Jacksonville (Alabama) | 3,998.31 mi (6,434.66 km) |
| Irvine to Jacksonville (Arkansas) | 4,180.13 mi (6,727.27 km) |
| Irvine to Jacksonville (Florida) | 4,024.20 mi (6,476.33 km) |
| Irvine to Jacksonville (Illinois) | 3,860.36 mi (6,212.65 km) |
| Irvine to Jacksonville (North Carolina) | 3,631.55 mi (5,844.41 km) |
