| Irvine to Indianola (Iowa) | 3,896.37 mi (6,270.60 km) |
| Irvine to Indio (California) | 5,071.53 mi (8,161.84 km) |
| Irvine to Inglewood (California) | 5,124.36 mi (8,246.87 km) |
| Irvine to Inkster (Michigan) | 3,481.63 mi (5,603.14 km) |
| Irvine to Inver Grove Heights (Minnesota) | 3,705.51 mi (5,963.44 km) |
| Irvine to Inwood (New York) | 3,202.18 mi (5,153.41 km) |
| Irvine to Iona (Florida) | 4,238.44 mi (6,821.12 km) |
| Irvine to Ionia (Michigan) | 3,512.95 mi (5,653.55 km) |
| Irvine to Iowa City (Iowa) | 3,809.71 mi (6,131.14 km) |
| Irvine to Irmo (South Carolina) | 3,809.65 mi (6,131.04 km) |
| Irvine to Irondale (Alabama) | 4,046.34 mi (6,511.96 km) |
| Irvine to Ironton (Ohio) | 3,641.92 mi (5,861.10 km) |
| Irvine to Irvine (California) | 5,122.98 mi (8,244.64 km) |
| Irvine to Irving (Texas) | 4,464.57 mi (7,185.03 km) |
| Irvine to Isabela (Puerto Rico) | 4,098.42 mi (6,595.78 km) |
