| Irvine to Hutchinson (Minnesota) | 3,747.56 mi (6,031.12 km) |
| Irvine to Hutto (Texas) | 4,611.26 mi (7,421.10 km) |
| Irvine to Hyattsville (Maryland) | 3,404.23 mi (5,478.58 km) |
| Irvine to Hybla Valley (Virginia) | 3,419.46 mi (5,503.09 km) |
| Irvine to Idaho Falls (Idaho) | 4,389.94 mi (7,064.92 km) |
| Irvine to Idylwood (Virginia) | 3,417.29 mi (5,499.59 km) |
| Irvine to Ilchester (Maryland) | 3,384.62 mi (5,447.01 km) |
| Irvine to Immokalee (Florida) | 4,222.55 mi (6,795.54 km) |
| Irvine to Imperial (California) | 5,102.28 mi (8,211.32 km) |
| Irvine to Imperial Beach (California) | 5,166.89 mi (8,315.30 km) |
| Irvine to Independence (Kentucky) | 3,690.99 mi (5,940.07 km) |
| Irvine to Independence (Missouri) | 4,040.83 mi (6,503.09 km) |
| Irvine to Indian Trail (North Carolina) | 3,739.10 mi (6,017.49 km) |
| Irvine to Indiana (Pennsylvania) | 3,407.25 mi (5,483.44 km) |
| Irvine to Indianapolis (Indiana) | 3,708.91 mi (5,968.91 km) |
