| Irvine to Elkhorn (Wisconsin) | 3,652.70 mi (5,878.45 km) |
| Irvine to Elko (Nevada) | 4,650.21 mi (7,483.80 km) |
| Irvine to Elkridge (Maryland) | 3,384.84 mi (5,447.37 km) |
| Irvine to Elkton (Maryland) | 3,329.73 mi (5,358.68 km) |
| Irvine to Ellensburg (Washington) | 4,434.78 mi (7,137.09 km) |
| Irvine to Ellicott City (Maryland) | 3,384.29 mi (5,446.49 km) |
| Irvine to Elmhurst (Illinois) | 3,669.39 mi (5,905.31 km) |
| Irvine to Elmira (New York) | 3,249.02 mi (5,228.79 km) |
| Irvine to Elmont (New York) | 3,196.69 mi (5,144.58 km) |
| Irvine to Elmwood Park (Illinois) | 3,663.57 mi (5,895.95 km) |
| Irvine to Elmwood Park (New Jersey) | 3,202.93 mi (5,154.61 km) |
| Irvine to Elon (North Carolina) | 3,643.40 mi (5,863.49 km) |
| Irvine to Eloy (Arizona) | 4,978.65 mi (8,012.36 km) |
| Irvine to Elwood (New York) | 3,175.85 mi (5,111.04 km) |
| Irvine to Elyria (Ohio) | 3,481.19 mi (5,602.44 km) |
