| Irvine to El Sobrante (California) | 5,101.96 mi (8,210.82 km) |
| Irvine to Eldersburg (Maryland) | 3,382.66 mi (5,443.86 km) |
| Irvine to Elfers (Florida) | 4,177.02 mi (6,722.27 km) |
| Irvine to Elgin (Illinois) | 3,676.16 mi (5,916.20 km) |
| Irvine to Elizabeth (New Jersey) | 3,216.94 mi (5,177.16 km) |
| Irvine to Elizabeth City (North Carolina) | 3,508.15 mi (5,645.83 km) |
| Irvine to Elizabethton (Tennessee) | 3,735.43 mi (6,011.59 km) |
| Irvine to Elizabethtown (Kentucky) | 3,803.10 mi (6,120.50 km) |
| Irvine to Elizabethtown (Pennsylvania) | 3,333.09 mi (5,364.08 km) |
| Irvine to Elk City (Oklahoma) | 4,416.32 mi (7,107.38 km) |
| Irvine to Elk Grove (California) | 4,954.50 mi (7,973.50 km) |
| Irvine to Elk Grove Village (Illinois) | 3,665.78 mi (5,899.50 km) |
| Irvine to Elk Plain (Washington) | 4,480.17 mi (7,210.14 km) |
| Irvine to Elk River (Minnesota) | 3,697.93 mi (5,951.24 km) |
| Irvine to Elkhart (Indiana) | 3,607.69 mi (5,806.01 km) |
