| Irvine to Culpeper (Virginia) | 3,468.06 mi (5,581.31 km) |
| Irvine to Culver City (California) | 5,123.11 mi (8,244.85 km) |
| Irvine to Cumberland (Maryland) | 3,439.20 mi (5,534.86 km) |
| Irvine to Cupertino (California) | 5,038.08 mi (8,108.01 km) |
| Irvine to Cutler Bay (Florida) | 4,225.91 mi (6,800.94 km) |
| Irvine to Cutlerville (Michigan) | 3,541.34 mi (5,699.24 km) |
| Irvine to Cuyahoga Falls (Ohio) | 3,469.67 mi (5,583.89 km) |
| Irvine to Cypress (California) | 5,123.05 mi (8,244.75 km) |
| Irvine to Cypress Gardens (Florida) | 4,148.10 mi (6,675.72 km) |
| Irvine to Cypress Lake (Florida) | 4,234.86 mi (6,815.35 km) |
| Irvine to D'Iberville (Mississippi) | 4,293.23 mi (6,909.29 km) |
| Irvine to Dakota Ridge (Colorado) | 4,382.90 mi (7,053.59 km) |
| Irvine to Dale City (Virginia) | 3,434.46 mi (5,527.23 km) |
| Irvine to Dallas (Georgia) | 3,958.22 mi (6,370.14 km) |
| Irvine to Dallas (Oregon) | 4,627.76 mi (7,447.66 km) |
