| Irvine to Cookeville (Tennessee) | 3,868.50 mi (6,225.75 km) |
| Irvine to Coolidge (Arizona) | 4,965.45 mi (7,991.12 km) |
| Irvine to Coon Rapids (Minnesota) | 3,696.80 mi (5,949.42 km) |
| Irvine to Cooper City (Florida) | 4,198.66 mi (6,757.09 km) |
| Irvine to Coos Bay (Oregon) | 4,742.29 mi (7,631.97 km) |
| Irvine to Copiague (New York) | 3,186.16 mi (5,127.64 km) |
| Irvine to Coppell (Texas) | 4,459.60 mi (7,177.03 km) |
| Irvine to Copperas Cove (Texas) | 4,593.15 mi (7,391.96 km) |
| Irvine to Coral Gables (Florida) | 4,216.55 mi (6,785.88 km) |
| Irvine to Coral Springs (Florida) | 4,185.56 mi (6,736.01 km) |
| Irvine to Coral Terrace (Florida) | 4,215.55 mi (6,784.27 km) |
| Irvine to Coralville (Iowa) | 3,809.90 mi (6,131.45 km) |
| Irvine to Coram (New York) | 3,161.46 mi (5,087.88 km) |
| Irvine to Corcoran (California) | 5,037.28 mi (8,106.72 km) |
| Irvine to Cordele (Georgia) | 4,019.42 mi (6,468.63 km) |
