| Irvine to Clarkston (Georgia) | 3,940.76 mi (6,342.04 km) |
| Irvine to Clarksville (Indiana) | 3,767.77 mi (6,063.65 km) |
| Irvine to Clarksville (Tennessee) | 3,915.34 mi (6,301.13 km) |
| Irvine to Clawson (Michigan) | 3,463.93 mi (5,574.65 km) |
| Irvine to Clay (Alabama) | 4,036.51 mi (6,496.13 km) |
| Irvine to Clayton (California) | 4,998.08 mi (8,043.63 km) |
| Irvine to Clayton (Missouri) | 3,919.11 mi (6,307.20 km) |
| Irvine to Clayton (North Carolina) | 3,625.14 mi (5,834.10 km) |
| Irvine to Clayton (Ohio) | 3,637.26 mi (5,853.60 km) |
| Irvine to Clearfield (Utah) | 4,521.68 mi (7,276.94 km) |
| Irvine to Clearlake (California) | 4,958.23 mi (7,979.49 km) |
| Irvine to Clearwater (Florida) | 4,191.09 mi (6,744.91 km) |
| Irvine to Cleburne (Texas) | 4,507.80 mi (7,254.61 km) |
| Irvine to Clemmons (North Carolina) | 3,680.43 mi (5,923.08 km) |
| Irvine to Clemson (South Carolina) | 3,841.51 mi (6,182.31 km) |
