| Irvine to Centralia (Illinois) | 3,881.32 mi (6,246.38 km) |
| Irvine to Centralia (Washington) | 4,514.31 mi (7,265.09 km) |
| Irvine to Centreville (Virginia) | 3,428.65 mi (5,517.87 km) |
| Irvine to Ceres (California) | 4,990.33 mi (8,031.16 km) |
| Irvine to Cerritos (California) | 5,121.02 mi (8,241.49 km) |
| Irvine to Chalco (Nebraska) | 3,995.38 mi (6,429.94 km) |
| Irvine to Chalmette (Louisiana) | 4,361.68 mi (7,019.45 km) |
| Irvine to Chambersburg (Pennsylvania) | 3,383.87 mi (5,445.81 km) |
| Irvine to Chamblee (Georgia) | 3,939.30 mi (6,339.69 km) |
| Irvine to Champaign (Illinois) | 3,769.95 mi (6,067.15 km) |
| Irvine to Champlin (Minnesota) | 3,699.83 mi (5,954.29 km) |
| Irvine to Chandler (Arizona) | 4,956.49 mi (7,976.70 km) |
| Irvine to Chanhassen (Minnesota) | 3,721.27 mi (5,988.80 km) |
| Irvine to Channahon (Illinois) | 3,704.35 mi (5,961.57 km) |
| Irvine to Channelview (Texas) | 4,562.59 mi (7,342.77 km) |
