| Irvine to Carson (California) | 5,128.58 mi (8,253.65 km) |
| Irvine to Carson City (Nevada) | 4,864.32 mi (7,828.37 km) |
| Irvine to Carteret (New Jersey) | 3,222.19 mi (5,185.61 km) |
| Irvine to Cartersville (Georgia) | 3,943.77 mi (6,346.89 km) |
| Irvine to Carthage (Missouri) | 4,140.68 mi (6,663.79 km) |
| Irvine to Cary (Illinois) | 3,664.88 mi (5,898.05 km) |
| Irvine to Cary (North Carolina) | 3,633.13 mi (5,846.95 km) |
| Irvine to Casa de Oro-Mount Helix (California) | 5,150.88 mi (8,289.54 km) |
| Irvine to Casa Grande (Arizona) | 4,974.93 mi (8,006.38 km) |
| Irvine to Casas Adobes (Arizona) | 4,982.18 mi (8,018.04 km) |
| Irvine to Cascades (Virginia) | 3,416.58 mi (5,498.45 km) |
| Irvine to Casper (Wyoming) | 4,247.61 mi (6,835.87 km) |
| Irvine to Casselberry (Florida) | 4,098.91 mi (6,596.56 km) |
| Irvine to Castaic (California) | 5,102.58 mi (8,211.80 km) |
| Irvine to Castle Pines (Colorado) | 4,382.65 mi (7,053.20 km) |
